English: During transcription initiation, proteins (dark grey semi-circles) bound to distant regions of the DNA can be brought into proximity with each other since the intervening DNA can loop back on itself. The basal transcription machinery can interact with distant activators and repressors many kilobases upstream or downstream of the open reading frame.
ognan – Tú mást ognarskrivað verkið á ein slíkan hátt sum er útgreinaður av høvundanum ella lisenseigaranum (men ikki á nakran hátt ið kundi bent á at hesin hevur góðkent teg ella tína nýtslu av verkinum).
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